Farnesylthiosalicylic acid-loaded lipid-polyethylene glycol-polymer hybrid nanoparticles for treatment of glioblastoma

KAFFASHI, MELİKE; Lule, SEVDA; PEHLIVAN, Sibel; SARISOZEN, Can; VURAL, İMRAN; KOSUCU, Husnu; Demir, Taner; Bugdayci, Kadir; Soylemezoglu, Figen; OGUZ, Kader; Mut, Melike

doi:10.1111/jphp.12740

Farnesylthiosalicylic acid-loaded lipid-polyethylene glycol-polymer hybrid nanoparticles for treatment of glioblastoma

KAFFASHI A., Lule S., PEHLIVAN S. B., SARISOZEN C., VURAL İ., KOSUCU H., ...Daha Fazla

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.69, sa.8, ss.1010-1021, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 69 Sayı: 8
Basım Tarihi: 2017
Doi Numarası: 10.1111/jphp.12740
Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1010-1021
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

ObjectivesWe aimed to develop lipid-polyethylene glycol (PEG)-polymer hybrid nanoparticles, which have high affinity to tumour tissue with active ingredient, a new generation antineoplastic drug, farnesylthiosalicylic acid (FTA) for treatment of glioblastoma.