Farnesylthiosalicylic acid-loaded lipid-polyethylene glycol-polymer hybrid nanoparticles for treatment of glioblastoma

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KAFFASHI A., Lule S., PEHLIVAN S. B., SARISOZEN C., VURAL İ., KOSUCU H., ...Daha Fazla

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.69, sa.8, ss.1010-1021, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 8
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/jphp.12740
  • Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1010-1021
  • Hacettepe Üniversitesi Adresli: Evet

Özet

ObjectivesWe aimed to develop lipid-polyethylene glycol (PEG)-polymer hybrid nanoparticles, which have high affinity to tumour tissue with active ingredient, a new generation antineoplastic drug, farnesylthiosalicylic acid (FTA) for treatment of glioblastoma.