Expressions of homeobox, collagen and estrogen genes in women with uterine prolapse

Dokmeci, Fulya; Teksen, Fulya; Cetinkaya, S.; Ozkan, Tulin; Kaplan, Fuat; Kose, Kenan

doi:10.1016/j.ejogrb.2018.11.019

Expressions of homeobox, collagen and estrogen genes in women with uterine prolapse

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Dokmeci F., Teksen F., Cetinkaya S. E., Ozkan T., Kaplan F., Kose K.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.233, pp.26-29, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 233
Publication Date: 2019
Doi Number: 10.1016/j.ejogrb.2018.11.019
Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.26-29
Hacettepe University Affiliated: Yes

Abstract

Objective: Genetic contribution is thought to be involved in the pathophysiology of pelvic organ prolapse (POP). We aimed to study the gene expression profiles of the genes HomeoboxA11 (HOXA11), HomeoboxA13 (HOXA13), Collagen Type I (COL1A), Collagen Type III (COL3A), estrogen receptor genes (ESR1 and ESR2) of round (RL) and uterosacral ligaments (USL) in postmenopausal women with uterine prolapse.