Effects of developmental exposure to silver in ionic and nanoparticle form: A study in rats

Charehsaz, ÜLKÜ; HOUGAARD, Karin; Sipahi, Hande; Ekici, Asiye; Kaspar, Cigdem; Culha, Mustafa; Bucurgat, Ulku; Aydin, Ahmet

doi:10.1186/s40199-016-0162-9

Effects of developmental exposure to silver in ionic and nanoparticle form: A study in rats

Charehsaz M., HOUGAARD K. S., Sipahi H., Ekici A. I. D., Kaspar C., Culha M., ...Daha Fazla

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.24, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 24
Basım Tarihi: 2016
Doi Numarası: 10.1186/s40199-016-0162-9
Dergi Adı: DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, developmental toxicity of Ag-NPs (from 0.2 to 20 mg/kg/day) and ionic Ag (AgNO3, 20 mg Ag/kg/day) were investigated in rats.