Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children

Schaefer, Franz; Trachtman, Howard; Wuhl, Elke; Kirchner, Marietta; Hayek, Salim; Anarat, Ali; DÜZOVA, ALİ; Mir, Sevgi; Paripovic, Dusan; Yilmaz, Alev; Lugani, Francesca; Arbeiter, Klaus; Litwin, Mieczyslaw; Oh, Jun; Matteucci, Maria; Gellermann, Jutta; Wygoda, Simone; Jankauskiene, Augustina; Klaus, Gunter; Dusek, Jiri; Testa, Sara; Zurowska, Aleksandra; Afonso, Alberto; Tracy, Melissa; Wei, Changli; Sever, Sanja; Smoyer, William; Reiser, Jochen

doi:10.1001/jamapediatrics.2017.2914

Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children

Atıf İçin Kopyala

Schaefer F., Trachtman H., Wuhl E., Kirchner M., Hayek S. S., Anarat A., ...Daha Fazla

JAMA PEDIATRICS, cilt.171, sa.11, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 171 Sayı: 11
Basım Tarihi: 2017
Doi Numarası: 10.1001/jamapediatrics.2017.2914
Dergi Adı: JAMA PEDIATRICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe Üniversitesi Adresli: Evet

Özet

IMPORTANCE Conventional methods to diagnose and monitor chronic kidney disease (CKD) in children, such as creatinine level and cystatin C-derived estimated glomerular filtration rate (eGFR) and assessment of proteinuria in spot or timed urine samples, are of limited value in identifying patients at risk of progressive kidney function loss. Serum soluble urokinase receptor (suPAR) levels strongly predict incident CKD stage 3 in adults.