Antithrombin III attenuates pulmonary tissue injury caused by mesenteric. ischemia-reperfusion
AMERICAN JOURNAL OF SURGERY, cilt.189, sa.2, ss.161-166, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 189 Sayı: 2
- Basım Tarihi: 2005
- Doi Numarası: 10.1016/j.amjsurg.2004.11.003
- Dergi Adı: AMERICAN JOURNAL OF SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.161-166
- Hacettepe Üniversitesi Adresli: Hayır
Özet
Background: Mesenteric ischemia-reperfusion (I/R) is a well-known event causing both local and remote organ injuries, including the lungs. Recently, several studies indicated that activated leukocyte-endothelial cell interactions play an important role in the mechanisms of these injuries. As a natural inhibitor of serine proteases, antithrombin was shown previously to attenuate the tissue damage after local I/R in several organ systems. Here, we examined the effects of antithrombin on pulmonary injury after mesenteric I/R.