Clinical and pharmacological variables as a risk factor for nifedipine-induced gingival overgrowth

GÜNCÜ G. N., ÇAĞLAYAN F., Dincel A., Bozkurt A., ÖZMEN F., KARABULUT E.

AUSTRALIAN DENTAL JOURNAL, vol.52, no.4, pp.295-299, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1834-7819.2007.tb00505.x
  • Journal Name: AUSTRALIAN DENTAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.295-299
  • Hacettepe University Affiliated: Yes

Abstract

Background. Gingival enlargement is usually noted within one to two months after the initiation of nifedipine therapy. The aetiology of nifedipine-induced gingival overgrowth is uncertain. The aim of this study was to determine the relationship between plasma and gingival crevice fluid (GCF) nifedipine concentrations and the degree of gingival overgrowth in patients treated with nifedipine, and also to assess the correlations between clinical and pharmacological variables.