Microvascular invasion in hepatocellular carcinoma

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Unal E., Idilman I. S., Akata D., Ozmen M. N., Karcaaltincaba M.

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY, vol.22, no.2, pp.125-132, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 22 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.5152/dir.2015.15125
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.125-132
  • Hacettepe University Affiliated: Yes


Microvascular invasion is a crucial histopathologic prognostic factor for hepatocellular carcinoma. We reviewed the literature and aimed to draw attention to clinicopathologic and imaging findings that may predict the presence of microvascular invasion in hepatocellular carcinoma. Imaging findings suggesting microvascular invasion are disruption of capsule, irregular tumor margin, peritumoral enhancement, multifocal tumor, increased tumor size, and increased glucose metabolism on positron emission tomography-computed tomography. In the presence of typical findings, microvascular invasion may be predicted.