The Effect of Infusion Speed on Nephrotoxicity in Patients Receiving Colistine Treatment in Oncology Hospital


HABİLOĞLU A. D. , Toros G. Y. , Askin T., Tuncel Y. I. , Duygu F., Unver S., ...More

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, vol.24, no.2, pp.87-92, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.5578/flora.67631
  • Title of Journal : FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI
  • Page Numbers: pp.87-92

Abstract

Introduction: infections with multi-resistant gram-negative bacteria have recently become a major problem, and colistin is one of the best alternatives for patients who cannot be treated using broad-spectrum antibiotics. However, colistin has many side effects including nephrotoxicity. Colistin can be administered as long or short infusions according to its pharmacokinetic/pharmacodynamic properties. In the present study, it was aimed to investigate the effect of mode of colistin administration on nephrotoxicity in patients in the intensive care unit.