Allergic reactions against Covid-19 vaccines


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ÜNSAL H., ŞEKEREL B. E., ŞAHİNER Ü. M.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.51, sa.5, ss.2233-2242, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 51 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3906/sag-2104-329
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.2233-2242
  • Anahtar Kelimeler: COVID-19, vaccine, allergy, hypersensitiviy, polyethylene glycol, REVISED NOMENCLATURE, POLYETHYLENE-GLYCOLS, LOCAL REACTIONS, ANAPHYLAXIS, CHILDREN, VACCINATION, RISK, HYPERSENSITIVITY, RECOMMENDATIONS, LIPOSOMES
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Coronavirus Disease 2019 (COVID-19) affected the whole world in a short time. One of the most influential public health initiatives modern medicine has to offer, the vaccine has become even more important as the COVID-19 pandemic continues to worsen worldwide. Many vaccine trials were launched during the COVID-19 pandemic, and these vaccines were widely used around the world, offering realistic hope for ending the pandemic. Allergic reactions to vaccines were reported shortly after their approval. These reactions, in general, are rare, but, in some circumstances, they can be serious. Allergy to vaccines can occur because of either the active vaccine component or vaccine ingredients. The spectrum of the reactions may be just a local hypersensitiviy reaction or may be as severe as an anaphylaxis, which is an acute severe, life-threatening systemic hypersensitive reaction, and it requires quick intervention. If an allergy is suspected, a correct examination followed by algorithms is important for true diagnosis, treatment, and decision regarding revaccination. Patients who experience an allergic reaction with the first dose of covid 19 vaccine should be directed to the allergy -immunologist, and the evaluation of at-risk patients should be individualized. Finally, we should point out that the benefits of current COVID-19 vaccines go far beyond the side effects, and that the vaccine is the most important way to recover from the pandemic.