Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

Seyhan, Nevra; Keskin, Suat; Aktan, Murat; AVUNDUK, MUSTAFA; ŞENGELEN, MELTEM; Savaci, Nedim

doi:10.1097/scs.0000000000002728

Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

Seyhan N., Keskin S., Aktan M., AVUNDUK M. C., ŞENGELEN M., Savaci N.

JOURNAL OF CRANIOFACIAL SURGERY, cilt.27, sa.5, ss.1367-1370, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 5
Basım Tarihi: 2016
Doi Numarası: 10.1097/scs.0000000000002728
Dergi Adı: JOURNAL OF CRANIOFACIAL SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1367-1370
Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: In previous studies, it has been shown that both simvastatin (chlolesterollowering drug) and platelet-rich plasma (PRP) were capable of promoting bone formation. The aim of this study was to compare the effects of PRP and simvastatin on healing of critical-size bone defects.