Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects


Seyhan N., Keskin S., Aktan M., AVUNDUK M. C. , ŞENGELEN M. , Savaci N.

JOURNAL OF CRANIOFACIAL SURGERY, vol.27, no.5, pp.1367-1370, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.1097/scs.0000000000002728
  • Title of Journal : JOURNAL OF CRANIOFACIAL SURGERY
  • Page Numbers: pp.1367-1370

Abstract

Objective: In previous studies, it has been shown that both simvastatin (chlolesterollowering drug) and platelet-rich plasma (PRP) were capable of promoting bone formation. The aim of this study was to compare the effects of PRP and simvastatin on healing of critical-size bone defects.