A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience

Pauli, Chantal; Bochtler, Tilmann; Mileshkin, Linda; Baciarello, Giulia; Losa, Ferran; Ross, Jeffrey; Pentheroudakis, George; Zarkavelis, George; YALÇIN, ŞUAYİB; ÖZGÜROĞLU, Mustafa; Beringer, Andreas; Scarato, Jeremy; Mueller-Ohldach, Mathis; Thomas, Marlene; Moch, Holger; Kramer, Alwin

doi:10.1002/onco.13744

A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience

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Pauli C., Bochtler T., Mileshkin L., Baciarello G., Losa F., Ross J. S., ...More

ONCOLOGIST, vol.26, no.5, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 26 Issue: 5
Publication Date: 2021
Doi Number: 10.1002/onco.13744
Journal Name: ONCOLOGIST
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
Keywords: Cancer of unknown primary, Diagnosis, Histology, Molecularly guided therapy, Comprehensive genomic profiling, Next&#8208, generation sequencing, PRIMARY SITE, BOSNIAK CLASSIFICATION, DIAGNOSIS, EXPRESSION, CARCINOMA, ORIGIN, NEOPLASMS, SPREAD
Hacettepe University Affiliated: Yes

Abstract

Background CUPISCO is an ongoing randomized phase II trial (NCT03498521) comparing molecularly guided therapy versus platinum-based chemotherapy in patients newly diagnosed with "unfavorable" cancer of unknown primary (CUP).