Environmental asbestos exposure and nonmalignant pleural findings: a retrospective evaluation of a five-year chest CT repository

Sandal A., Ecin S. M., Koyuncu A., DURHAN G., GÜLSÜN AKPINAR M., DEMİR A. U., ...Daha Fazla

ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH, cilt.77, sa.9, ss.734-743, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 9
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/19338244.2021.2004987
  • Dergi Adı: ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Environment Index, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.734-743
  • Anahtar Kelimeler: Asbestos, environment, environmental exposure, PLAQUES, MESOTHELIOMA, WORKERS, DIAGNOSIS, EXPOSOME, PREVALENCE, MANAGEMENT, SOUTHEAST, DISEASES, CANCER
  • Hacettepe Üniversitesi Adresli: Evet

Özet

This registry-based case-control study aimed to assess the association between asbestos deposits in the birthplace and/or residence and nonmalignant pleural findings, namely pleural plaques (PPs) and pleural thickening (PT), on chest CT scans. In total, 39,472 CT scans obtained over five years in a tertiary referral hospital in Ankara, Turkey, were evaluated. Cases involving patients with PP (n = 537), PT (n = 263), PP&PT (n = 69), and controls (n = 543) from the same study base without those conditions were included. Each case group was compared to controls using unconditional logistic regression. The presence of asbestos deposits in the district of birthplace (adjusted OR = 2.13, 95% CI: 1.35-3.37) and both birthplace and residence (aOR = 4.32, 95% CI: 2.26-8.27) was significantly related to the PPs. As the importance of environmental asbestos exposure in Turkey continues, future prospective studies could contribute to developing screening strategies.