SCE FREQUENCY OF HERPES-SIMPLEX VIRUS TYPE-I INFECTED-CELLS

TEZEL A., ATABEY N., EMRE S., SAKIZLI M.

MUTATION RESEARCH, vol.306, no.1, pp.81-83, 1994 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 306 Issue: 1
  • Publication Date: 1994
  • Doi Number: 10.1016/0027-5107(94)90169-4
  • Journal Name: MUTATION RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.81-83
  • Keywords: PERIPHERAL BLOOD LYMPHOCYTES, SISTER-CHROMATID EXCHANGE, HERPES SIMPLEX VIRUS TYPE-I, SISTER CHROMATID EXCHANGE, LYMPHOCYTES
  • Hacettepe University Affiliated: Yes

Abstract

The effects of herpes simplex virus type I (HSV-I) on SCE frequencies in human lymphocytes in vitro were investigated. SCE frequencies in controls (mean +/- ISD 5.2 +/- 1.6) and in cells exposed to the virus for 3 and 6 h (mean +/- ISD 5.3 +/- 1.6 and 5.8 +/- 1.6 respectively) were about the same. However, cells infected for 9 and 24 h showed a significant increase of SCE frequencies (p < 0.05).