Resveratrol Protects Sepsis-Induced Oxidative DNA Damage in Liver and Kidney of Rats
BALKAN MEDICAL JOURNAL, cilt.33, sa.6, ss.594-601, 2016 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 6
- Basım Tarihi: 2016
- Doi Numarası: 10.5152/balkanmedj.2016.15516
- Dergi Adı: BALKAN MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.594-601
- Anahtar Kelimeler: Resveratrol, sepsis, tumor necrosis factor alpha oxidative stress, DNA damage, alkaline single cell gel electrophoresis, HUMAN-LYMPHOCYTES, CRITICALLY-ILL, STRESS, PREVENTION, PARAMETERS, MELATONIN, INJURY, MOUSE, CELLS
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: The increases of free radicals have been proposed to be involved in the pathogenesis of sepsis, which leads to multiple-organ dysfunction syndromes. The uses of antioxidants as a complementary tool in the medical care of oxidative stress-related diseases have attracted attention of researchers. Resveratrol (RV) has suggested being antioxidant, anti-proliferative, and anti-inflammatory effects in various experimental models and clinical settings.