Global fibrinolytic capacity is decreased in girls with premature adrenarche: A new pathological finding?

Andiran, N; Yordam, NURŞEN; Kirazli, S

doi:10.1515/jpem.2005.18.12.1373

Global fibrinolytic capacity is decreased in girls with premature adrenarche: A new pathological finding?

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Andiran N., Yordam N., Kirazli S.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, vol.18, no.12, pp.1373-1381, 2005 (SCI-Expanded)

Publication Type: Article / Article
Volume: 18 Issue: 12
Publication Date: 2005
Doi Number: 10.1515/jpem.2005.18.12.1373
Journal Name: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1373-1381
Hacettepe University Affiliated: Yes

Abstract

Objective: Global fibrinolytic capacity (GFC) is a sensitive method reflecting all of the molecular components involved in the process of fibrinolysis. Recently, a decrease in GFC has been shown in women with polycystic ovary syndrome (PCOS). Girls with premature adrenarche (PA) have been shown to have hyperinsulinemia and dyslipidemia in addition to hyperandrogenemia, similar to women with PCOS. The aim of this study was to evaluate GFC levels in girls with PA.