Global fibrinolytic capacity is decreased in girls with premature adrenarche: A new pathological finding?

Andiran, N; Yordam, NURŞEN; Kirazli, S

doi:10.1515/jpem.2005.18.12.1373

Global fibrinolytic capacity is decreased in girls with premature adrenarche: A new pathological finding?

Andiran N., Yordam N., Kirazli S.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.18, sa.12, ss.1373-1381, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 12
Basım Tarihi: 2005
Doi Numarası: 10.1515/jpem.2005.18.12.1373
Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1373-1381
Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Global fibrinolytic capacity (GFC) is a sensitive method reflecting all of the molecular components involved in the process of fibrinolysis. Recently, a decrease in GFC has been shown in women with polycystic ovary syndrome (PCOS). Girls with premature adrenarche (PA) have been shown to have hyperinsulinemia and dyslipidemia in addition to hyperandrogenemia, similar to women with PCOS. The aim of this study was to evaluate GFC levels in girls with PA.