Background: Suicide events observed in various groups, community or countries, especially in the periods of economic recession. It is thought that suicide cases increase when people's income decreases dramatically and they lose their jobs. Aim/Objective: In this study, it was aimed to investigate whether the 2008 economic crisis had any effect on suicides in the United States. Methods: Autoregressive distributed lag method was used. For the purpose of the study, the number of suicide-related deaths was taken as the dependent variable, while unemployment rates and 2008 economic crisis were taken as independent variables. Findings: The short-term and long-term relationships obtained within the scope of the study indicated that the 2008 economic crisis had a statistically significant effect on suicide cases in the United States. Results and Conclusion: It can be said that the results of this study are consistent with the information which emphasizes that economic crises increase suicide cases in the literature.