The effect of Pseudomonas aeruginosa eradication regimens on chronic colonization and clinical outcomes in pediatric patients with cystic fibrosis

Buyuksahin H. N., Yalcin E., EMİRALİOĞLU ORDUKAYA N., HAZIROLAN G., Tural D. A., Ozsezen B., ...Daha Fazla

PEDIATRICS INTERNATIONAL, cilt.64, sa.1, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1111/ped.15249
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: body mass index, cystic fibrosis, lung function, Pseudomonas aeruginosa, LONGITUDINAL DEVELOPMENT, DORNASE-ALPHA, LUNG-FUNCTION, CHILDREN, INFECTION, ECFS, ACQUISITION, GUIDELINES, NUTRITION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Chronic Pseudomonas aeruginosa colonization (Pa-CC) affects cystic fibrosis (CF) progression, including pulmonary exacerbations and pulmonary function tests. There are few studies of the effects of eradication protocols on colonization time. Here, we aimed to evaluate the effect of eradication regimens on chronic colonization and assess the impact of Pa-CC on body mass index, lung functions, and pulmonary exacerbations.