Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant.

Gökçe, M; Aytaç, ŞEVKİYE; Ünal, ŞULE; Altan, İ; Gümrük, FATMA; Çetin, M

doi:10.4274/tjh.2013.0189

Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant.

Gökçe M., Aytaç Ş. S., Ünal Ş., Altan İ., Gümrük F., Çetin M.

Turkish journal of haematology : official journal of Turkish Society of Haematology, cilt.32, sa.1, ss.64-7, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 32 Sayı: 1
Basım Tarihi: 2015
Doi Numarası: 10.4274/tjh.2013.0189
Dergi Adı: Turkish journal of haematology : official journal of Turkish Society of Haematology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.64-7
Hacettepe Üniversitesi Adresli: Evet

Özet

© 2015, Turkish Society of Hematology. All rights reserved.Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we report a 3-month-old infant presenting with a pelvic mass and pancytopenia suggesting neuroblastoma. Bone marrow evaluation revealed t(1;22)-positive AMKL that responded well to a regimen containing high-dose cytarabine.