Systemic Administration of Interleukin-10 Attenuates Early Ischemic Response Following Spinal Cord Ischemia Reperfusion Injury in Rats


Oruckaptan H. H. , Ozisik P., ATİLLA P. , Tuncel M., Kilinc K., Geyik P. , ...More

JOURNAL OF SURGICAL RESEARCH, vol.155, no.2, pp.345-356, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 155 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jss.2008.07.013
  • Title of Journal : JOURNAL OF SURGICAL RESEARCH
  • Page Numbers: pp.345-356

Abstract

Background. The aim of this experimental study was to investigate the early effects of interleukin-10 (IL-10) and interleukin-1 beta antagonist (anti-IL-1 beta) against cellular damage, inflammatory reactivity, lipid peroxidation (LPO), and myeloperoxidase (MPO) activity induced by spinal cord ischemia reperfusion injury (IRI).