Systemic Administration of Interleukin-10 Attenuates Early Ischemic Response Following Spinal Cord Ischemia Reperfusion Injury in Rats


Oruckaptan H. H. , Ozisik P., ATİLLA P. , Tuncel M., Kilinc K., Geyik P. O. , ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.155, ss.345-356, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 155 Konu: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jss.2008.07.013
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.345-356

Özet

Background. The aim of this experimental study was to investigate the early effects of interleukin-10 (IL-10) and interleukin-1 beta antagonist (anti-IL-1 beta) against cellular damage, inflammatory reactivity, lipid peroxidation (LPO), and myeloperoxidase (MPO) activity induced by spinal cord ischemia reperfusion injury (IRI).