International randomized phase 2 study on the addition of docetaxel to the combination of cisplatin and 5-fluorouracil in the induction treatment for nasopharyngeal carcinoma in children and adolescents

CASANOVA, Michela; Ozyar, Enis; PATTE, Catherine; ORBACH, Daniel; FERRARI, Andrea; VEYRAT-FOLLET, Christine; ERRIHANI, Hassan; PAN, Jianji; ZHANG, LI; SHEN, Liji; GRZEGORZEWSKI, Krzysztof; VARAN, ALİ

doi:10.1007/s00280-015-2933-2

International randomized phase 2 study on the addition of docetaxel to the combination of cisplatin and 5-fluorouracil in the induction treatment for nasopharyngeal carcinoma in children and adolescents

CASANOVA M., Ozyar E., PATTE C., ORBACH D., FERRARI A., VEYRAT-FOLLET C., ...Daha Fazla

CANCER CHEMOTHERAPY AND PHARMACOLOGY, cilt.77, sa.2, ss.289-298, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 77 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.1007/s00280-015-2933-2
Dergi Adı: CANCER CHEMOTHERAPY AND PHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.289-298
Hacettepe Üniversitesi Adresli: Evet

Özet

Nasopharyngeal carcinoma (NPC) is a rare but aggressive malignancy in children and adolescents. An international, randomized phase 2 trial was conducted to compare induction chemotherapy with docetaxel plus cisplatin and 5-fluorouracil (TPF) with cisplatin and 5-fluorouracil (PF) in NPC patients under the age of 21.