L-Arginine Add-On Treatment for Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
TURK PSIKIYATRI DERGISI, vol.29, no.3, 2018 (SSCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 29 Issue: 3
- Publication Date: 2018
- Doi Number: 10.5080/u22702
- Journal Name: TURK PSIKIYATRI DERGISI
- Journal Indexes: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
- Hacettepe University Affiliated: Yes
Abstract
Introduction: Current drug treatments for schizophrenia are only partially effective and combination/augmentation strategies are commonly used. Nitric Oxide (NO) may play a role in the pathophysiology of schizophrenia. L-arginine is the precursor of NO. In this study, we aimed to investigate whether L-arginine add-on to current medication might improve positive, negative, and depressive symptoms in schizophrenia/schizoaffective disorder patients in partial remission.