Synthesis, crystal structure and Hirshfeld surface analysis of 3-[5-(4-chloro­phen­yl)-2-sulfanyl­idene-1,3,4-oxa­diazol-3-yl]-3-(4-methyl­phen­yl)-1-(thio­phen-2-yl)propan-1-one

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Jain S., Kumar S., HÖKELEK T.

Acta Crystallographica Section E: Crystallographic Communications, cilt.82, ss.1107-1111, 2026 (ESCI, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 82
• Basım Tarihi: 2026
• Doi Numarası: 10.1107/s2056989026008819
• Dergi Adı: Acta Crystallographica Section E: Crystallographic Communications
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
• Sayfa Sayıları: ss.1107-1111
• Anahtar Kelimeler: 4-chloro­phen­yl, 4-oxa­diazol, crystal structure
• Hacettepe Üniversitesi Adresli: Evet

Özet

The title thio­phene-chalcone derivative, C22H17ClN2O2S2, contains a planar oxa­diazole, a thio­phene and two phenyl rings. The dihedral angle between the oxa­diazole and thio­phene rings is 27.45 (10)°, and they are oriented with respect to the chloro­phenyl and methyl­phenyl rings at 22.61 (10), 67.07 (8) and 49.16 (10), 87.22 (8)°, respectively, while the phenyl rings are oriented at 51.78 (9)°. In the crystal, π–π stacking inter­actions and C—H⋯π(ring) inter­actions help to consolidate the packing. Hirshfeld surface analysis revealed that the most important contributions to the crystal packing are from H⋯H (31.6%), H⋯C/C⋯H (20.0%), H⋯S/S⋯H (14.2%) and H⋯O/O⋯H (9.5%) inter­actions.