Alteration of the microRNA expression profile in familial Mediterranean fever patients

Akkaya-Ulum Y. Z., Balci-Peynircioglu B., KARADAĞ Ö., Eroglu F. K., KALYONCU U., KİRAZ S., ...Daha Fazla

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.35, sa.6, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 6
  • Basım Tarihi: 2017
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: inflammation, epigenetics, microRNAs, familial Mediterranean fever, array, inflammatory pathways, INFLAMMATION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective. Phenotypic heterogeneity in familial Mediterranean fever (FMF) disease indicated that FMF is not a simple monogenic disease. Therefore it has been suggested that epigenetic factors can be one of the reason for the variations. We undertook this study to test potential involvement of miRNAs in the pathogenesis of FMF.