Obesity is associated with increased myocardial oxidative stress

VINCENT H., POWERS S., STEWART D., SHANELY R., Demirel H., NAITO H.

INTERNATIONAL JOURNAL OF OBESITY, cilt.23, sa.1, ss.67-74, 1999 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1038/sj.ijo.0800761
  • Dergi Adı: INTERNATIONAL JOURNAL OF OBESITY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.67-74
  • Anahtar Kelimeler: obesity, myocardium, lipid peroxidation, antioxidant enzymes, reactive oxygen species (ROS), ZUCKER-FATTY RAT, FREE-RADICALS, CELLULAR DEFENSES, SKELETAL-MUSCLE, ISCHEMIA, EXERCISE, PROTEINS, HEART, ASSAY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

OBJECTIVE: To determine: 1) whether obesity predisposes the myocardium to oxidative stress as evidenced by higher tissue levels of myocardial lipid peroxidation, and 2) what cellular mechanisms are responsible for this predisposition.