Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation

Akboga M. K., Canpolat U., Sahinarslan A., Alsancak Y., Nurkoc S., Aras D., ...Daha Fazla

ATHEROSCLEROSIS, cilt.240, sa.1, ss.110-114, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 240 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.atherosclerosis.2015.02.051
  • Dergi Adı: ATHEROSCLEROSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.110-114
  • Anahtar Kelimeler: Bilirubin, Inflammation, CRP, NLR, RDW, Atherosclerosis, LOW-DENSITY-LIPOPROTEIN, CELL DISTRIBUTION WIDTH, C-REACTIVE PROTEIN, LYMPHOCYTE RATIO, ENDOTHELIAL FUNCTION, INVERSE RELATIONSHIP, ARTERY-DISEASE, NEUTROPHIL, METAANALYSIS, RISK
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Although cardiovascular protective action of bilirubin has been attributed to its antioxidant effect, there was scarce data regarding the anti-inflammatory properties. Herein, we aimed to assess the relationship between serum total bilirubin level and severity of coronary artery disease (CAD) in association with the direct inflammatory marker such as C-reactive protein (CRP), the other indirect markers included in inflammation process such as neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) in patients with stable CAD.