Ultrastructural changes of epidermal langerhans cells in pregnant guinea pigs: A preliminary report

ALP H., DURGUN B., MUFTUOGLU S. F., INAN S., ASAN E.

Cells Tissues Organs, cilt.149, sa.2, ss.100-103, 1994 (Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 149 Sayı: 2
  • Basım Tarihi: 1994
  • Doi Numarası: 10.1159/000147563
  • Dergi Adı: Cells Tissues Organs
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.100-103
  • Anahtar Kelimeler: Electron microscopy, Langerhans cells, Pregnancy
  • Hacettepe Üniversitesi Adresli: Evet

Özet

An association between pregnancy and a depression in cellular immunity has long been known, but the reason for this is far from clear. To investigate the possible role of Langerhans cells (LC) in immunosuppression during pregnancy, we examined the epidermal LC morphology of pregnant guinea pigs ultrastructurally. An altered morphology of epidermal LCs was observed in all specimens obtained from pregnant guinea pigs. LCs were found to be activated in pregnancy. © 1994 S. Karger AG, Basel.