PTEN Expression in Primary Prostate Carcinoma in Turkish Patients


Baydar D. E., Ozen H., Saracbasi O., KARABULUT E.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.38, sa.5, ss.387-397, 2008 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 5
  • Basım Tarihi: 2008
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.387-397
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Aim: Prostatic adenocarcinoma shows remarkable variability in the incidence and biological behavior between populations from different races and geographical regions of the world. PTEN has been reported as the most commonly mutated tumor suppressor gene in prostate cancer. Incidence of PTEN alterations occurring in prostatic carcinoma has not been studied previously in the Turkish population.