Possible effects of dietary advanced glycation end products on maternal and fetal health: a review

Demirer B., SAMUR F. G.

NUTRITION REVIEWS, cilt.81, sa.7, ss.844-856, 1 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 81 Sayı: 7
  • Basım Tarihi: 1
  • Doi Numarası: 10.1093/nutrit/nuac090
  • Dergi Adı: NUTRITION REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Agricultural & Environmental Science Database, CAB Abstracts, CINAHL, EMBASE, Environment Index, Food Science & Technology Abstracts, Hospitality & Tourism Complete, Hospitality & Tourism Index, MEDLINE, Pollution Abstracts, SportDiscus, Veterinary Science Database
  • Sayfa Sayıları: ss.844-856
  • Anahtar Kelimeler: advanced glycation end products, fetal health, maternal health, nutrition pregnancy
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Excessive accumulation of advanced glycation end products (AGEs) in the body has been associated with many adverse health conditions. The common point of the pathologies associated at this point is oxidative stress and inflammation. Pregnancy is an important period in which many physiological, psychological, and biological changes are experienced. Along with the physiological changes that occur during this period, the mother maintaining an AGE-rich diet may cause an increase in the body's AGE pool and may increase oxidative stress and inflammation, as seen in healthy individuals. Studies have reported the negative effects of maternal AGE levels on maternal and fetal health during pregnancy. Although gestational diabetes, preeclampsia, endothelial dysfunction, and pelvic diseases constitute maternal complications, a number of pathological conditions such as intrauterine growth retardation, premature birth, neural tube defect, neurobehavioral developmental disorders, fetal death, and neonatal asphyxia constitute fetal complications. It is thought that the mechanisms of these complications have not been confirmed yet and more clinical studies are needed on this subject. The possible effects of dietary AGE levels during pregnancy on maternal and fetal health are examined in this review.