Infantile atopic dermatitis: Serum vitamin D, zinc and TARC levels and their relationship with disease phenotype and severity

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ESENBOĞA S., Sahiner N., Birben E., UYSAL SOYER Ö., ŞEKEREL B. E., ŞAHİNER Ü. M.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.49, sa.3, ss.162-168, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.15586/aei.v49i3.191
  • Dergi Adı: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.162-168
  • Anahtar Kelimeler: atopic dermatitis, infant, objective SCORAD, TARC, vitamin D, 0-1 year, ACTIVATION-REGULATED CHEMOKINE, CHILDREN, THYMUS, AGE
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Several markers that influence the clinical course of atopic dermatitis (AD) have been investigated so far. Thymus and activation regulated chemokine (TARC) - a Th2-related cytokine - increase in various atopic diseases. It has been shown that vitamin D affects Treg cells and immune responses. Zinc as an essential trace element for cell-cell interactions, cellular differentiation, and proliferation. However, the effect of these markers on infantile AD and disease severity are mostly unknown.