CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T-1 breast cancer

Cabioglu N., Yazici M. S., Arun B., Broglio K., Hortobagyi G., Price J., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.11, sa.16, ss.5686-5693, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 16
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1158/1078-0432.ccr-05-0014
  • Dergi Adı: CLINICAL CANCER RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5686-5693
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose: The chemokine receptors CCR7 and CXCR4 have been shown to play an important role in cancer metastasis. We therefore studied the differential expression of CCR7 and CXCR4, along with that of the biomarker HER2-neu, to evaluate whether these biomarkers could predict axillary lymph node metastasis in breast cancer.