Can the Combination of Simvastatin and Melatonin Create a Synergistic Effect on Bone Regeneration?

KOÇ, ONUR; TÜZ, HAKAN; Ocak, Mert; Bilecenoglu, Burak; FIRAT, AYŞEGÜL; KAYMAZ, FEVZİYE

doi:10.1016/j.joms.2020.12.044

Can the Combination of Simvastatin and Melatonin Create a Synergistic Effect on Bone Regeneration?

KOÇ O. , TÜZ H. H. , Ocak M., Bilecenoglu B., FIRAT A. , KAYMAZ F. F.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, vol.79, no.8, pp.1672-1682, 2021 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 79 Issue: 8
Publication Date: 2021
Doi Number: 10.1016/j.joms.2020.12.044
Title of Journal : JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
Page Numbers: pp.1672-1682

Abstract

Purpose: The present study evaluated the potential bone regeneration capacity of combining melatonin and simvastatin, with a goal of producing more osteogenic bone substitutes.