Reduced irisin levels in patients with acromegaly

Şendur S. N., Baykal G., Fırlatan B., Aydin B., Lay İ., Dağdelen S., ...Daha Fazla

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION, cilt.43, sa.3, ss.251-261, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1515/hmbci-2022-0009
  • Dergi Adı: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.251-261
  • Anahtar Kelimeler: acromegaly, FNDC5 polymorphism, irisin, somatostatin receptor ligand, ADIPOSE-TISSUE, DIABETES-MELLITUS, FNDC5, METABOLISM, GLUCOSE, GENE, CONSENSUS, CRITERIA, SERUM, CURE
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives: Several metabolic disturbances are seen in acromegaly however, data regarding the contribution of irisin to these disturbances is currently insufficient. In a cohort of patients with acromegaly, we measured serum irisin levels in active and controlled cases and determined independent factors that effect serum irisin including fibronectin type III domain-containing protein 5 (FNDC5) genotyping.