Hepatoprotective and antioxidant effects of lycopene in acute cholestasis

Tokac, Mehmet; Aydin, SEVTAP; Taner, Gokce; Ozkardes, Alper; Yavuz Taslipinar, MİNE; DOGAN, Mehmet; Dundar, Halit; Kilic, Mehmet; BAŞARAN, ARİF; BAŞARAN, AYŞE

doi:10.3906/sag-1404-57

Hepatoprotective and antioxidant effects of lycopene in acute cholestasis

Tokac M., Aydin S., Taner G., Ozkardes A. B., Yavuz Taslipinar M., DOGAN M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.4, ss.857-864, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 45 Sayı: 4
Basım Tarihi: 2015
Doi Numarası: 10.3906/sag-1404-57
Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.857-864
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background/aim: Lycopene, which is suggested to be a potent antioxidant, may play a protective role in diseases related to oxidative stress. In order to understand the effects of lycopene in the pathogenesis of cholestasis, we investigated the effects of lycopene on oxidative stress parameters and DNA damage induced by experimental biliary obstruction in the liver tissues and the lymphocytes of Wistar albino rats.