REVISTA ESPANOLA DE MEDICINA NUCLEAR, vol.27, no.3, pp.191-198, 2008 (Peer-Reviewed Journal)
Article / Article
REVISTA ESPANOLA DE MEDICINA NUCLEAR
Science Citation Index Expanded, Scopus, DIALNET
thalassemia major, cardiac toxicity, atherosclerosis, Tc-99m tetrofosmin, scintigraphy, LEFT-VENTRICULAR FUNCTION, BETA-THALASSEMIA, IRON OVERLOAD, ATHEROSCLEROTIC LESIONS, CARDIOMYOPATHY, ECHOCARDIOGRAPHY, SPECT, DYSFUNCTION, TOMOGRAPHY, INFARCTION
Objective. Iron overload limits the life expectancy of thalassaemic patients by causing cardiac toxicity. Iron also plays a catalytic role in the pathogenesis of atherosclerosis. The aim of this study was to evaluate the role of Tc-99m Tetrofosmin gated myocardial perfusion scintigraphy (GMPS) in the detection of cardiac dysfunction in patients with thalassemia major.