Invasive Mould Infections in Intensive Care Units: Epidemiology, Microbiologic Diagnosis and Antifungal Resistance


Sig A. K., ARIKAN AKDAĞLI S.

JOURNAL OF MEDICAL AND SURGICAL INTENSIVE CARE MEDICINE, cilt.10, sa.2, ss.63-69, 2019 (ESCI) identifier identifier

Özet

Invasive fungal infections present with a rising incidence and high morbidity and mortality rates. Among these infections are those due to moulds which draw particular attention per the diagnostic difficulties and higher mortality rates. While a relative decrease is observed in mortality rates regarding the use of prophylactic, empirical or preemptive antifungal regimens, there is a tendency of increase in antifungal resistance rates. Furthermore, due to increase in number of cases with immunosuppression, infections caused by rare and emerging moulds are now more frequently observed. Breakthrough infections, nosocomial infections, and infections due to risk factors other than immunosuppression are also a clinical concern.