ALOX5 promoter genotype, asthma severity and LTC4 production by eosinophils

---

Copy For Citation

KALAYCI Ö., Birben E., Sackesen C., KESKİN Ö., TAHAN F., WECHSLER M. E., ...More

ALLERGY, vol.61, no.1, pp.97-103, 2006 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 61 Issue: 1
• Publication Date: 2006
• Doi Number: 10.1111/j.1398-9995.2006.00979.x
• Journal Name: ALLERGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.97-103
• Hacettepe University Affiliated: Yes

Abstract

Background: The number of Sp1-Egr1 binding tandem repeats at the ALOX5 promoter influences gene transcription and may modify the response to anti-leukotriene treatment. The relationship of ALOX5 variants to asthma severity and leukotriene production by eosinophils is unknown.