Copy For Citation
Okar S., TOPÇUOĞLU M. A., Yemisci M., Aktas C., Oguz K. K., ARSAVA E. M.
Journal of neuroimmunology, vol.344, pp.577247, 2020 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
344
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Publication Date:
2020
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Doi Number:
10.1016/j.jneuroim.2020.577247
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Journal Name:
Journal of neuroimmunology
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
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Page Numbers:
pp.577247
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Keywords:
Cerebrovascular diseases, Immunology, Infections, Neuroimaging, Strokes, ISCHEMIC-STROKE, MOTOR RECOVERY, BRAIN, IMMUNE, INJURY, CLASSIFICATION, PATHOLOGY, OUTCOMES, ATROPHY, PROTEIN
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Hacettepe University Affiliated:
Yes
Abstract
Objectives: There is a delicate homeostatic balance between the central nervous system and immune system. Stroke triggers an immunodepressive state to suppress a potential immune reaction directed against neuroglial tissue; however, this supposedly protective response inadvertently results in an infection-prone, and thereby a pro-inflammatory setting. In this study, we assessed the magnitude of cerebral volume loss in the unaffected contralateral hemisphere following stroke, and determined its relationship with inflammatory cascades.