Diagnosis, management strategies and research horizons in sarcopenia

Razaq S., KARA M., ÖZÇAKAR L., Rathore F. A.

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, cilt.72, sa.5, ss.998-1001, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 5
  • Basım Tarihi: 2022
  • Doi Numarası: 10.47391/jpma.22-68
  • Dergi Adı: JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.998-1001
  • Anahtar Kelimeler: Muscle mass, lean mass, geriatrics, rehabilitation intervention, muscle power, PHYSICAL FUNCTION, WOMEN
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Sarcopenia was first described by Rosenberg as the age-related loss of skeletal muscle mass. The early operational definitions of sarcopenia were based on low muscle mass alone. However, research has suggested a strong predictive relationship between measures of muscle quality i.e., strength and/or physical performance, and health outcomes. Therefore, the definition has been revised to "age-related loss of muscle mass and muscle function". The etiology of sarcopenia is multifactorial and diagnostic recommendations published to date have addressed the total or appendicular muscle mass. Measurement of anterior thigh muscle mass has better correlations with functional tests and all-cause mortality when compared with appendicular or total muscle mass measurements. The aim of this review is to highlight the importance of sarcopenia as an emerging public health issue, diagnostic evaluation with muscle mass and functional performance evaluations and appropriate interventions for management.