Acute Invasive Fulminant Fungal Rhinosinusitis: An Evaluation of 25 Cases

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Eroğlu E., Pamuk A. E., Özer S., Önerci T. M.

ENT UPDATES, cilt.14, sa.2, ss.42-47, 2024 (ESCI)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.5152/entupdates.2024.24396
  • Dergi Adı: ENT UPDATES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Sayfa Sayıları: ss.42-47
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Hacettepe Üniversitesi Adresli: Evet

Özet

 Background: Acute invasive fungal rhinosinusitis (AIFRS) is a severe infection that affects the nasal cavity and paranasal sinuses, often seen in individuals with comor bidities such as diabetes mellitus and hemato-oncological diseases. This study aims to retrospectively analyze patients diagnosed with AIFRS from 2014 to 2023. Methods: The study was a single-center, descriptive investigation focusing on demo graphic details, clinical presentation, radio-pathological features, and suggested management of AIFRS patients. Results: Of the 25 patients involved in the study, with a mean age of 48 years, hemato oncological diseases were the most common underlying condition (44%), followed by diabetes mellitus (28%). Fungal analysis revealed Aspergillus species (32%) and Mucor (24%). The most frequently involved site was the middle turbinate (84%), while the least affected was the inferior turbinate (36%). The mortality rate was 48%, primar ily due to underlying hemato-oncological diseases (32%). Aspergillus (16%) and Mucor (16%) were the most commonly encountered pathogens in fatal cases. Conclusion: Patients with diabetes mellitus, hemato-oncological diseases, or second ary immunodeficiency undergoing steroid treatment should be vigilantly screened for AIFRS. Early diagnosis and prompt management are crucial to improve patient outcomes