Akademik Veri Yönetim Sistemi
Anatolian Journal of Clinical Investigation, cilt.3, sa.1, ss.4-9, 2009 (Scopus)
Carotid artery disease is a major cause of ischemic stroke. Many stenoses are inaccessible surgically and many patients are considered high risk to undergo carotid endarterectomy (CEA). Carotid artery stenting (CS) is an evolving technique for the treatment of carotid artery disease and is the leading alternative to CEA. Diffusion weighted MRI (DWI) offers the possibility of making even small and therefore asymptomatic distal embolic lesions visible. We prospectively examined 14 patients who underwent CEA and 12 patients who underwent CS from September 2004 to August 2005. DWI was performed on the day before as well as the day after the intervention. Distal embolic lesions were detected at DWI in one patient of CEA group and in one of CS group, which revealed no statistical difference. No post procedural complication was observed. We observed no significant difference regarding post-interventional DWI-lesions. Therefore CEA as well CS are suitable methods for treatment of carotid artery stenosis and DWI studies should serve as an additional surrogate endpoint of further studies to enable an objective comparison of both methods.