Preliminary data on growth and reproduction parameters of Cobitis simplicispina from Daryozu Creek in the Kizilirmak basin in Kirsehir-Turkey were presented. The age of the specimens collected during a period between March and June 2002, ranged from 1(+) to 4(+). The observed maximum total length of males is 91.8 mm, and 97 mm for females. The von Bertalanffy equation for male and female specimens was found to be Lt = 93.01 (1-exp(-0.408(t + 0.821))) and Lt = 94.42(1-exp(-0.488(t + 0.458))), respectively. The length-weight relationship was expressed as log W = 3.009x SL -5.171 when all specimens were taken into account. The range of absolute fecundity extended from 320 to 2141 eggs and the diameter of ripe eggs varied between 1.00 and 1.25 mm. The gonadosomatic index suggested that spawning took place in April.