Colchicine and Leukopenia: Clinical Implications

Sag E., Bayindir Y., Adiguzel A., Demir S., Bilginer Y., Aytac Ş. S., ...Daha Fazla

JOURNAL OF PEDIATRICS, cilt.224, ss.166-171, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 224
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jpeds.2020.03.065
  • Dergi Adı: JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Sociological abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.166-171
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Colchicine is the mainstay of treatment for familial Mediterranean fever. We investigated the frequency of leukopenia in 213 patients with familial Mediterranean fever treated with standard doses of colchicine (0.5-2.0 mg/day). We found that 23 patients (10.8%) had reversible leukopenia, 3 moderate, and none severe and that their rate of infections was not increased.