Addition of intramuscular progesterone to vaginal progesterone in hormone replacement therapy in vitrified-warmed blastocyst transfer cycles

Polat M., MÜMÜŞOĞLU S., BOZDAĞ G., Ozbek I. Y., Humaidan P., Yarali H.

REPRODUCTIVE BIOMEDICINE ONLINE, vol.40, no.6, pp.812-818, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.1016/j.rbmo.2020.01.0311472-6483
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.812-818
  • Keywords: Cryopreserved embryo transfer, Hormone replacement therapy, Im progesterone supplementation, IVF, Serum progesterone, Vaginal progesterone supplementation, SERUM PROGESTERONE, EMBRYO-TRANSFER, IMPLANTATION, ENDOMETRIN, RATES
  • Hacettepe University Affiliated: Yes


Research question: Does intramuscular progesterone supplementation ensure ongoing pregnancy rates (OPR) comparable with vaginal progesterone only in hormone replacement therapy cycles for vitrified-warmed embryo transfer; and is there a window of serum progesterone concentration out of which reproductive outcomes may be negatively affected?