Serum resistin and high sensitive CRP levels in patients with subclinical hypothyroidism before and after L-thyroxine therapy

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Aksoy D. Y., Cinar N., Harmanci A., Karakaya J., Yildiz B. O., Usman A., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.19, ss.210-215, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19
  • Basım Tarihi: 2013
  • Doi Numarası: 10.12659/msm.883847
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.210-215
  • Anahtar Kelimeler: resistin, high-sensitive-CRP, subclinical hypothyroidism, C-REACTIVE PROTEIN, CARDIOVASCULAR RISK-FACTORS, LOW-GRADE INFLAMMATION, NECROSIS-FACTOR-ALPHA, INSULIN-RESISTANCE, THYROID-FUNCTION, ADIPONECTIN, OBESITY, LEPTIN, EXPRESSION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Subclinical hypothyroidism (SH) is defined by increased thyrotropin (TSH) and normal free thyroxine (fT4) and free triiodothyronine (fT3) levels. Resistin is secreted from adipose tissue and is reported to be associated with insulin resistance and/or inflammation. High sensitive CRP (hs-CRP) is a reliable marker of inflammation. Data related to levels of resistin and hs-CRP in SH and the effect of L-thyroxine treatment on those is limited. We aimed to determine the levels of resistin and hs-CRP in women with SH, and potential effects of L-thyroxine therapy on those levels.