Chronic Hemolysis, Oxidative Stress and Inflammation Contribute to Dysfunctional HDL in Sickle Cell Disease


Yalcinkaya A., Unal S., Oztas Y.

Blood, cilt.130, sa.S1, ss.2240-2241, 2017 (SCI-Expanded)

  • Yayın Türü: Makale / Özet
  • Cilt numarası: 130 Sayı: S1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1182/blood.v130.suppl_1.2240.2240
  • Dergi Adı: Blood
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2240-2241
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Hypocholesterolemia was observed in sickle cell disease (SCD) patients according to various reports in the literature. It was previously linked to anemia and inflammation by others and to oxidative stress by our group. In this study we investigated the relationship between cholesterol metabolism, hemolysis, inflammation and oxidative stress in SCD.