The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.

Sackesen C., Karaaslan C., KESKİN Ö., TOKOL N., TAHAN F., Civelek E., ...Daha Fazla

Allergy, cilt.60, sa.12, ss.1485-92, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 12
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1398-9995.2005.00874.x
  • Dergi Adı: Allergy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1485-92
  • Anahtar Kelimeler: asthma, CD14, endotoxin, IgE, TLR4, TOLL-LIKE RECEPTOR-4, HOUSE-DUST ENDOTOXIN, SERUM IGE LEVELS, ATOPIC ASTHMA, LIPOPOLYSACCHARIDE, EXPOSURE, ASSOCIATION, HYPORESPONSIVENESS, CHALLENGE, MUTATIONS
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Endotoxin, with its potential to enhance type 1 immunity, is a significant player in the hygiene hypothesis. The combined effects of the genetic variants of various molecules in the endotoxin response pathway on asthma related phenotypes are largely unknown.