Synchrotron FT-IR microspectroscopic analysis of necrotic bone


Bayari S. H. , UTKU H. , IKEMOTO Y., Celasun B., Koemuercue M., ATIK A.

SPECTROSCOPY-AN INTERNATIONAL JOURNAL, vol.21, no.4, pp.227-234, 2007 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1155/2007/732013
  • Title of Journal : SPECTROSCOPY-AN INTERNATIONAL JOURNAL
  • Page Numbers: pp.227-234

Abstract

Avascular necrosis (osteonecrosis) is a disease that results from the temporary or permanent loss of blood supply to the bone. Synchrotron FT-IR microspectroscopy has been used to study the changes in mineral and matrix content of necrotic bone. FT-IR spectroscopic analysis revealed that in necrotic bone the relative mineral/matrix ratio decreased. Spectroscopic differences were observed between normal and necrotic bones. The noticeable differences may have important implications for analyzing and evaluating death bone.