The association of timothy grass allergy and cat ownership on cat sensitization

CAN BOSTAN Ö., Cakmak M. E., Kaya S. B., TUNCAY G., DAMADOĞLU E., KARAKAYA G., ...More

ALLERGY AND ASTHMA PROCEEDINGS, vol.43, no.3, pp.220-225, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.2500/aap.2022.43.220012
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.220-225
  • Hacettepe University Affiliated: Yes


Background: Pollen hypersensitivity might be a determining factor for other nonseasonal allergens because it may indicate deviation of the immune system toward T-helper type 2 activity and immunoglobulin E sensitivity. Objective: To investigate whether timothy grass pollen allergy may be a predictive factor for cat sensitization and whether Method: A retrospective review was made of patients with symptoms of rhinitis. The skin-prick test results and cat ownership status of the patients were analyzed. On the basis of the skin-prick test results with Phleum pratense (timothy grass) and other pollens, the patients were analyzed in two groups: ???timothy allergic??? and ???non???timothy allergic.??? Results: A total of 383 patients with the diagnosis of rhinitis were included in the study, which comprised 213 (55.6%) in the timothy allergic group and 170 (44.4%) in the non???timothy allergic group. The frequency of cat sensitization was significantly higher in the patients in the timothy allergic group compared with those without timothy grass allergy (33.8% versus 12.3%; p < 0.001). No significant difference was determined between the two groups in terms of cat ownership (p = 0.63). In the logistic regression analysis, cat ownership (adjusted odds ratio [OR] 23.07 [95% confidence interval {CI}, 7.72???68.91]) and timothy allergy (adjusted OR 7.72 [95% CI, 3.16???18.86]) were associated with an increased risk of cat sensitization. Conclusion: Timothy grass allergy may play a role in the development of cat sensitization; however, further research is needed to clarify these associations and the underlying mechanisms. (Allergy Asthma Proc 43:220???225, 2022; doi: 10.2500/aap.2022.43.220012)