Purpose: The purposes of this study were to evaluate patients' adherence to home exercise programs in physiotherapy practice in Turkey, and to learn which factors of patients', therapists', care or surroundings have an effect on patients' adherence to home exercises. Material and methods: Eighty two out-patients have participated in this study. Fifty eight subjects were females (70.7%) and 24 (27.3%) were males. Subjects' age ranged from 16 to 75 years old. Seventy five (91.4%) of the subjects had exercises prescribed to them in a range of one week to several months ago. Demographics, personal, treatment/disease, patient therapist communication data was collected by means of a questionnaire, specially developed for this study. Twenty-five questions were presented with answers on a 5-point scale. Subjects were evaluated during treatment visits to physiotherapy clinics. Results: Hundred percent adherence to home exercises was found in 39% of the cases. Following factors were found to have correlation with adherence: "gender", "external motivation", "exercises role in overall rehabilitation", "understanding of exercises", physiotherapist's "verbal" and "visual" explanation, "physiotherapist's explanation quality", "reassessment of home exercises" and "satisfaction with physiotherapist" (p<0.05). Conclusion: This study reconfirmed the adherence rate to home prescribed exercises and found a number of a new factors that have an effect on the process. Based on these findings a physiotherapist should re-think and re-evaluate the time spent on explaining home exercises to patients.