Procaine and saline have similar effects on articular cartilage and synovium in rat knee

Ankay Y., Akca B., Buyukakkus B., Bahador Z., Zeybek D., Uzumcugil F., ...Daha Fazla

BMC ANESTHESIOLOGY, cilt.18, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1186/s12871-018-0513-9
  • Dergi Adı: BMC ANESTHESIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Procaine, Rats, Knee joint, Intra-articular injections, Local anaesthetics, LOCAL-ANESTHETICS, INTRAARTICULAR INJECTION, IN-VITRO, BUPIVACAINE, LEVOBUPIVACAINE, PAIN, MITOCHONDRIA, APOPTOSIS, LIDOCAINE, THERAPY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Intra-articular local anaesthetics are widely used for providing postoperative analgesia and decreasing the need for opioids. Procaine has proven positive effects in carpal tunnel syndrome and chondromalacia patella. However, the effect of procaine on articular cartilage has not yet been studied. The aim of this study was to evaluate the effects of intra-articular procaine injection on the articular cartilage and the synovium.